GENEVAC B 1ML — ADVANCED RECOMBINANT HEPATITIS B PROTECTION

Genevac B is a high-precision, non-infectious recombinant DNA vaccine specifically engineered to provide robust, long-term immunity against the Hepatitis B Virus (HBV). It contains the purified surface antigen of the virus ($HBsAg$), produced through advanced genetic engineering in yeast cells (Saccharomyces cerevisiae). This vaccine works by stimulating the body’s immune system to produce specific protective antibodies ($anti-HBs$) without any risk of causing the disease itself. Hepatitis B is a leading cause of chronic liver disease, cirrhosis, and liver cancer; Genevac B is the clinical gold standard for preventing these life-threatening complications.

• Product Type: Recombinant Hepatitis B Vaccine (rDNA)

• Active Component: Purified Hepatitis B Surface Antigen ($HBsAg$) — (20mcg per 1ml)

• Manufacturer: Serum Institute of India (SII)

• Form: Liquid Suspension in a 1ml Single-Dose Vial

• Route: Intramuscular (IM) Injection Only (Must NOT be given intravenously)

• Availability: Prescription/Clinic Use Only — Administered by healthcare professionals

• Suitable For: Adults and adolescents (20mcg dose)

What Is Genevac B Used For?

Genevac B is a foundational vaccine for universal and targeted immunization:

1. Primary Prevention: Providing lifelong immunity against all known subtypes of the Hepatitis B virus.

2. Occupational Safety: Essential for healthcare workers, laboratory staff, and first responders at risk of needle-stick injuries or blood exposure.

3. High-Risk Protection: Protecting individuals with multiple sexual partners, those receiving frequent blood transfusions, or those traveling to high-endemic areas.

4. Post-Exposure Prophylaxis: If administered immediately after exposure (alongside Hepatitis B Immune Globulin), it can prevent the virus from establishing a chronic infection.

⚠️ Critical Safety Warning

Yeast Allergy: Do NOT administer Genevac B to anyone with a history of severe allergic reaction (anaphylaxis) to Baker’s Yeast, as the vaccine is produced in yeast cells. Injection Site: In adults, the vaccine must be injected into the deltoid muscle (upper arm). Do not inject into the buttock (gluteal muscle), as this significantly reduces the immune response. Illness: Postpone vaccination if the patient has a moderate-to-severe acute fever. Bleeding Disorders: Use with caution in patients with hemophilia or those on blood thinners; a fine-gauge needle and firm pressure after injection are required to prevent bruising.

Immunization Schedule

For maximum, lifelong protection, the full 3-dose series must be completed to reach the protective antibody threshold of $10 \text{ mIU/mL}$.

Standard 3-Dose Schedule (Adults):

• 1st Dose: At the elected date.

• 2nd Dose: 1 month after the first dose.

• 3rd Dose: 6 months after the first dose.

Accelerated Schedule (For Rapid Protection):

• Doses at 0, 1, and 2 months, with a booster at 12 months if high risk persists.

Application Tips:

• Shake Well: The vaccine is a slightly opaque white suspension. Shake the vial well before withdrawal to ensure the antigen is evenly mixed.

• No Freezing: Never use a vial that has been accidentally frozen, as this destroys the vaccine's potency.

• Verification: For high-risk individuals, a blood test ($Anti-HBs$ titer) is recommended 1–2 months after the final dose to confirm successful immunity.

Common Side Effects

Most reactions are mild and transient, including soreness, redness, or slight swelling at the injection site. Some patients may experience a mild headache, fatigue, or a low-grade fever within 48 hours. These are normal signs that the immune system is activating. If you experience a high fever, severe dizziness, or signs of an allergic reaction (hives/difficulty breathing), seek emergency care immediately.

Storage & Cold Chain Management

• Strict Refrigeration: Genevac B must be stored between 2°C and 8°C.

• Freeze Protection: It is highly sensitive to freezing; if the liquid looks "clumpy" or has been frozen, it must be discarded.

• Light Sensitivity: Keep in the original carton to protect from light.

• Cold Chain Integrity: Sanlive Pharmacy utilizes 24/7 temperature-monitored medical refrigerators to ensure every 1ml vial maintains its full protective strength until the moment of injection.

Frequently Asked Questions (FAQ)

Q: Can I get Hepatitis B from the vaccine?

A: No. The vaccine contains only a purified protein (antigen) from the virus's surface; it contains no live virus and cannot cause infection.

Q: What if I "Miss a Dose"?

A: You do not need to restart the series. Simply take the missed dose as soon as possible and follow the original spacing for any remaining doses.

Q: Does it protect against Hepatitis A or C?

A: No. Genevac B specifically protects only against Hepatitis B. Separate vaccines or precautions are needed for other types of hepatitis.

Q: Is it safe during "Pregnancy"?

A: Yes. Because it is an inactivated (non-live) vaccine, it is generally considered safe for pregnant or breastfeeding women who are at high risk for the virus.

Purchase & Administration Notice at Sanlive Pharmacy

Authentic Genevac B 1ml (Adult Dose) is available through Sanlive Pharmacy. As a Cold-Chain product, we provide specialized delivery to clinics and hospitals. We can also assist you in scheduling your 1-month and 6-month reminders to ensure your series is completed on time.

Why Choose Sanlive Pharmacy for Vaccines?

• Authentic Serum Institute of India (SII) stock with verified batch integrity.

• Strict 24/7 Cold Chain temperature monitoring and backup power.

• Expert guidance on adult and pediatric immunization schedules.

• Reliable, temperature-controlled delivery within Lagos and across Nigeria.

Order Genevac B from Sanlive Pharmacy today to secure your long-term liver health and protection.